{"metadata":{"accession":"PF06738","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010619","hierarchy":null,"name":{"name":"Putative threonine/serine exporter","short":"ThrE"},"description":[{"text":"<p>ThrE is a family of bacterial and Archaeal proteins that catalyse the export of L-threonine from the cell [[cite:PUB00075540]]. UniProtKB:Q79VD1 has been characterised as being necessary for this export. The domain exhibits 10 putative TMs and catalyses the proton-motive-force-dependent efflux of threonine and serine [[cite:PUB00075541]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075540":{"PMID":12089010,"ISBN":null,"volume":"68","issue":"7","year":2002,"title":"Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicum.","URL":null,"raw_pages":"3321-7","medline_journal":"Appl Environ Microbiol","ISO_journal":"Appl. Environ. Microbiol.","authors":["Simic P","Willuhn J","Sahm H","Eggeling L."],"DOI_URL":"http://dx.doi.org/10.1128/AEM.68.7.3321-3327.2002"},"PUB00075541":{"PMID":12111147,"ISBN":null,"volume":"59","issue":"2-3","year":2002,"title":"Influence of threonine exporters on threonine production in Escherichia coli.","URL":null,"raw_pages":"205-10","medline_journal":"Appl Microbiol Biotechnol","ISO_journal":"Appl. Microbiol. Biotechnol.","authors":["Kruse D","Kramer R","Eggeling L","Rieping M","Pfefferle W","Tchieu JH","Chung YJ","Jr Saier MH","Burkovski A."],"DOI_URL":"http://dx.doi.org/10.1007/s00253-002-0987-7"}},"set_info":{"accession":"CL0470","name":"ThrE"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":72,"interactions":0,"matches":13368,"pathways":0,"proteins":13070,"proteomes":9351,"sets":1,"structural_models":{"alphafold":8741},"structures":0,"taxa":13949},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":97,"alignment:full":7517},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}