{"metadata":{"accession":"PF06684","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009569","hierarchy":null,"name":{"name":"Amino acid synthesis","short":"AA_synth"},"description":[{"text":"<p>This family of proteins is structurally similar to proteins with the Bacillus chorismate mutase-like (BCM-like) fold. This structure, combined with its genomic context, suggest that it has a role in amino acid synthesis [[cite:PUB00057508]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057508":{"PMID":20944209,"ISBN":null,"volume":"66","issue":"Pt 10","year":2010,"title":"Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.","URL":null,"raw_pages":"1182-9","medline_journal":"Acta Crystallogr Sect F Struct Biol Cryst Commun","ISO_journal":"Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.","authors":["Bakolitsa C","Kumar A","Jin KK","McMullan D","Krishna SS","Miller MD","Abdubek P","Acosta C","Astakhova T","Axelrod HL","Burra P","Carlton D","Chen C","Chiu HJ","Clayton T","Das D","Deller MC","Duan L","Elias Y","Ellrott K","Ernst D","Farr CL","Feuerhelm J","Grant JC","Grzechnik A","Grzechnik SK","Han GW","Jaroszewski L","Johnson HA","Klock HE","Knuth MW","Kozbial P","Marciano D","Morse AT","Murphy KD","Nigoghossian E","Nopakun A","Okach L","Paulsen J","Puckett C","Reyes R","Rife CL","Sefcovic N","Tien HJ","Trame CB","Trout CV","van den Bedem H","Weekes D","White A","Xu Q","Hodgson KO","Wooley J","Elsliger MA","Deacon AM","Godzik A","Lesley SA","Wilson IA."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":2962,"pathways":0,"proteins":2961,"proteomes":1863,"sets":0,"structural_models":{"alphafold":1820},"structures":2,"taxa":2794},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":1416},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3byq","name":"Crystal structure of a duf1185 family protein (bb2672) from bordetella bronchiseptica rb50 at 1.70 A resolution"}}}