{"metadata":{"accession":"PF06542","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009497","hierarchy":null,"name":{"name":"Regulator protein PHA-1","short":"PHA-1"},"description":[{"text":"<p>This family represents the protein product of the gene pha-1 which coordinates with lin-35 Rb during animal development. The protein is expressed during embryonic development and functions in the cytoplasm. PHA-1 acts in a parallel pathway with UBC-18 to regulate the activity of a common cellular target [[cite:PUB00053702]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00053702":{"PMID":15196946,"ISBN":null,"volume":"271","issue":"1","year":2004,"title":"The coordinate regulation of pharyngeal development in C. elegans by lin-35/Rb, pha-1, and ubc-18.","URL":null,"raw_pages":"11-25","medline_journal":"Dev Biol","ISO_journal":"Dev. Biol.","authors":["Fay DS","Qiu X","Large E","Smith CP","Mango S","Johanson BL."],"DOI_URL":"http://dx.doi.org/10.1016/j.ydbio.2004.03.022"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":191,"pathways":0,"proteins":186,"proteomes":12,"sets":0,"structural_models":{"alphafold":182},"structures":0,"taxa":28},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":9,"alignment:full":161},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}