{"metadata":{"accession":"PF06497","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009477","hierarchy":null,"name":{"name":"Baculovirus Ac102","short":"Baculo_Ac102"},"description":[{"text":"<p>This family of baculovirus proteins is represented by Autographa californica nuclear polyhedrosis virus (AcMNPV) Ac102. Nuclear actin is critical for AcMNPV progeny production, and Ac102 plays an essential role in actin translocation to the nucleus [[cite:PUB00082590]]. It plays a role in regulating nuclear actin polymerisation as well as the morphogenesis and spatial distribution of viral capsid structures in the host nucleus [[cite:PUB00097495],[cite:PUB00097494]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00082590":{"PMID":22592260,"ISBN":null,"volume":"93","issue":"Pt 8","year":2012,"title":"Nuclear localization of actin requires AC102 in Autographa californica multiple nucleopolyhedrovirus-infected cells.","URL":null,"raw_pages":"1795-803","medline_journal":"J Gen Virol","ISO_journal":"J. Gen. Virol.","authors":["Gandhi KM","Ohkawa T","Welch MD","Volkman LE."],"DOI_URL":"http://dx.doi.org/10.1099/vir.0.041848-0"},"PUB00097494":{"PMID":29618641,"ISBN":null,"volume":"92","issue":"12","year":2018,"title":"Ac102 Participates in Nuclear Actin Polymerization by Modulating BV/ODV-C42 Ubiquitination during Autographa californica Multiple Nucleopolyhedrovirus Infection.","URL":null,"raw_pages":null,"medline_journal":"J Virol","ISO_journal":"J Virol","authors":["Zhang Y","Hu X","Mu J","Hu Y","Zhou Y","Zhao H","Wu C","Pei R","Chen J","Chen X","Wang Y."],"DOI_URL":null},"PUB00097495":{"PMID":29540600,"ISBN":null,"volume":"92","issue":"11","year":2018,"title":"Baculovirus AC102 Is a Nucleocapsid Protein That Is Crucial for Nuclear Actin Polymerization and Nucleocapsid Morphogenesis.","URL":null,"raw_pages":null,"medline_journal":"J Virol","ISO_journal":"J Virol","authors":["Hepp SE","Borgo GM","Ticau S","Ohkawa T","Welch MD."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":94,"pathways":0,"proteins":94,"proteomes":94,"sets":0,"structural_models":{"alphafold":88},"structures":1,"taxa":190},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":39,"alignment:full":70},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}