{"metadata":{"accession":"PF06485","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046760","hierarchy":null,"name":{"name":"RNA-binding protein Tab2/Atab2 N terminal","short":"Tab2-like_N"},"description":[{"text":"<p>This is the N-terminal domain of proteins from photosynthetic organisms including plants and cyanobacteria, such as Tab2 proteins. Tab2 was first identified in Chlamydomonas reinhardtii as a RNA binding protein required for translation of the chloroplast PsaB photosystem I subunit [[cite:PUB00083885]]. Later, the Tab2 homologue (ATAB2) from Arabidopsis was found involved in the signalling pathway of light-controlled synthesis of photosystem proteins during early plant development [[cite:PUB00083887]], presumably functioning as an activator of translation with targets at PSI and PSII [[cite:PUB00098288]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00083887":{"PMID":17139246,"ISBN":null,"volume":"25","issue":"24","year":2006,"title":"ATAB2 is a novel factor in the signalling pathway of light-controlled synthesis of photosystem proteins.","URL":null,"raw_pages":"5907-18","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Barneche F","Winter V","Crevecoeur M","Rochaix JD."],"DOI_URL":"http://dx.doi.org/10.1038/sj.emboj.7601472"},"PUB00098288":{"PMID":25725436,"ISBN":null,"volume":"1847","issue":"9","year":2015,"title":"Large-scale genetic analysis of chloroplast biogenesis in maize.","URL":null,"raw_pages":"1004-16","medline_journal":"Biochim Biophys Acta","ISO_journal":"Biochim Biophys Acta","authors":["Belcher S","Williams-Carrier R","Stiffler N","Barkan A."],"DOI_URL":null},"PUB00083885":{"PMID":14633996,"ISBN":null,"volume":"22","issue":"23","year":2003,"title":"Tab2 is a novel conserved RNA binding protein required for translation of the chloroplast psaB mRNA.","URL":null,"raw_pages":"6378-88","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Dauvillee D","Stampacchia O","Girard-Bascou J","Rochaix JD."],"DOI_URL":"http://dx.doi.org/10.1093/emboj/cdg591"}},"set_info":{"accession":"CL0219","name":"RNase_H"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":11,"interactions":0,"matches":1056,"pathways":0,"proteins":1052,"proteomes":697,"sets":1,"structural_models":{"alphafold":777},"structures":0,"taxa":1954},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":60,"alignment:full":757},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}