{"metadata":{"accession":"PF06381","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR024459","hierarchy":null,"name":{"name":"Phage portal protein","short":"Phage_portal_3"},"description":[{"text":"<p>This family represents phage and prophage portal proteins that form the portal of the phage particle [[cite:PUB00155786],[cite:PUB00153918],[cite:PUB00154413]]. These proteins form a dodecamer assembly that defines a channel for DNA entry and exit. The dodecamer structure resembles a flying saucer with a central channel, which is filled with a rope-like DNA chain [[cite:PUB00154413]]. Each subunit of the dodecamer is involved in interaction with capsomers. The dodecameric portal is connected with the neck, which comprises a dodecameric adaptor, a hexameric connector, and a hexameric terminator gp12, forming a continuous DNA injection channel at the center [[cite:PUB00154413]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00153918":{"PMID":37422479,"ISBN":null,"volume":"14","issue":"1","year":2023,"title":"High-resolution cryo-EM structure of the Pseudomonas bacteriophage E217.","URL":null,"raw_pages":"4052","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Li F","Hou CD","Lokareddy RK","Yang R","Forti F","Briani F","Cingolani G."],"DOI_URL":"https://doi.org/10.1038/s41467-023-39756-z"},"PUB00154413":{"PMID":36656854,"ISBN":null,"volume":"120","issue":"4","year":2023,"title":"Fine structure and assembly pattern of a minimal myophage Pam3.","URL":null,"raw_pages":"e2213727120","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["Yang F","Jiang YL","Zhang JT","Zhu J","Du K","Yu RC","Wei ZL","Kong WW","Cui N","Li WF","Chen Y","Li Q","Zhou CZ."],"DOI_URL":"https://doi.org/10.1073/pnas.2213727120"},"PUB00155786":{"PMID":37866476,"ISBN":null,"volume":"435","issue":"24","year":2023,"title":"Structure of the Borrelia Bacteriophage φBB1 Procapsid.","URL":null,"raw_pages":"168323","medline_journal":"J Mol Biol","ISO_journal":"J Mol Biol","authors":["Rumnieks J","Fuzik T","Tars K."],"DOI_URL":"https://doi.org/10.1016/j.jmb.2023.168323"}},"set_info":{"accession":"CL0838","name":"Phage_portal"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":16,"interactions":0,"matches":1451,"pathways":0,"proteins":1449,"proteomes":1186,"sets":1,"structural_models":{"alphafold":637},"structures":13,"taxa":2536},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":22,"alignment:full":687},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}