Family of bacterial and archaeal proteins with unknown function. Some members are associated with a C-terminal peptidoglycan binding domain. So perhaps this could be an enzyme involved in peptidoglycan metabolism.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0052","name":"NTN"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":18,"interactions":0,"matches":4487,"pathways":0,"proteins":4479,"proteomes":3724,"sets":1,"structural_models":{"alphafold":2969},"structures":1,"taxa":5630},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":110,"alignment:full":2167},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2imh","name":"Crystal structure of protein SPO2555 from Silicibacter pomeroyi, Pfam DUF1028"}}}