{"metadata":{"accession":"PF06255","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR064118","hierarchy":null,"name":{"name":"Neisseria toxin MafB","short":"MafB"},"description":[{"text":"<p>MafB constitutes a family of secreted toxins in pathogenic Neisseria species, probably involved in interbacterial competition [[cite:PUB00073618]]. Genes immediately downstream of mafB encode a specific immunity protein (MafI). MafB proteins exhibit a signal peptide sequence, a N-terminal conserved domain and a C-terminal variable region. Toxic domains identified at the C terminus include [pfam:PF15542], [pfam:PF14437], [pfam:PF15524], and [pfam:PF14436].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00073618":{"PMID":25569427,"ISBN":null,"volume":"11","issue":"1","year":2015,"title":"A new family of secreted toxins in pathogenic Neisseria species.","URL":null,"raw_pages":"e1004592","medline_journal":"PLoS Pathog","ISO_journal":"PLoS Pathog.","authors":["Jamet A","Jousset AB","Euphrasie D","Mukorako P","Boucharlat A","Ducousso A","Charbit A","Nassif X."],"DOI_URL":"http://dx.doi.org/10.1371/journal.ppat.1004592"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":42,"pathways":0,"proteins":42,"proteomes":12,"sets":0,"structural_models":{"alphafold":36},"structures":0,"taxa":30},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":35},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}