{"metadata":{"accession":"PF06254","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009364","hierarchy":null,"name":{"name":"Bacterial toxin ydaT","short":"YdaT_toxin"},"description":[{"text":"<p>YdaT_toxin was first thought to be neutralised by the putative antitoxin YdaS ([pfam:PF15943]) [[cite:PUB00075651]] but recent studies showed that both YdaS and YdaT can act independently as toxins and are regulated by RacR [[cite:PUB00099919]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075651":{"PMID":21927020,"ISBN":null,"volume":"9","issue":"11","year":2011,"title":"Regulation of growth and death in Escherichia coli by toxin-antitoxin systems.","URL":null,"raw_pages":"779-90","medline_journal":"Nat Rev Microbiol","ISO_journal":"Nat. Rev. Microbiol.","authors":["Yamaguchi Y","Inouye M."],"DOI_URL":"http://dx.doi.org/10.1038/nrmicro2651"},"PUB00099919":{"PMID":29205229,"ISBN":null,"volume":"2","issue":"6","year":2017,"title":"CRISPR-Cas-Mediated Gene Silencing Reveals RacR To Be a Negative Regulator of YdaS and YdaT Toxins in <i>Escherichia coli</i> K-12.","URL":null,"raw_pages":null,"medline_journal":"mSphere","ISO_journal":"mSphere","authors":["Bindal G","Krishnamurthi R","Seshasayee ASN","Rath D."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":365,"pathways":0,"proteins":365,"proteomes":270,"sets":0,"structural_models":{"alphafold":173},"structures":2,"taxa":474},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":135},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}