{"metadata":{"accession":"PF06201","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010400","hierarchy":null,"name":{"name":"PITH domain","short":"PITH"},"description":[{"text":"<p>This family was formerly known as DUF1000. The full-length, Txnl1, protein which is a probable component of the 26S proteasome, uses its C-terminal, PITH, domain to associate specifically with the 26S proteasome. PITH derives from proteasome-interacting thioredoxin domain.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00038340":{"PMID":15741346,"ISBN":null,"volume":"14","issue":"4","year":2005,"title":"Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein.","URL":null,"raw_pages":"1059-63","medline_journal":"Protein Sci","ISO_journal":"Protein Sci.","authors":["Song J","Tyler RC","Wrobel RL","Frederick RO","Vojtek FC","Jeon WB","Lee MS","Markley JL."],"DOI_URL":"http://dx.doi.org/10.1110/ps.041246805"},"PUB00053806":{"PMID":19349277,"ISBN":null,"volume":"284","issue":"22","year":2009,"title":"Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome.","URL":null,"raw_pages":"15246-54","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Andersen KM","Madsen L","Prag S","Johnsen AH","Semple CA","Hendil KB","Hartmann-Petersen R."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M900016200"}},"set_info":{"accession":"CL0202","name":"GBD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":170,"interactions":0,"matches":8206,"pathways":0,"proteins":8085,"proteomes":3410,"sets":1,"structural_models":{"alphafold":6894},"structures":9,"taxa":9033},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":288,"alignment:full":6359},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}