{"metadata":{"accession":"PF06048","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009270","hierarchy":null,"name":{"name":"Domain of unknown function (DUF927)","short":"DUF927"},"description":[{"text":"<p>This entry represents a domain found in bacterial proteins of unknown  function. The crystal structure has been solved for a protein containing this domain SWISS:Q0WXP6 [[cite:PUB00085154]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00085154":{"PMID":27571176,"ISBN":null,"volume":"23","issue":"10","year":2016,"title":"Staphylococcal SCCmec elements encode an active MCM-like helicase and thus may be replicative.","URL":null,"raw_pages":"891-898","medline_journal":"Nat Struct Mol Biol","ISO_journal":"Nat. Struct. Mol. Biol.","authors":["Mir-Sanchis I","Roman CA","Misiura A","Pigli YZ","Boyle-Vavra S","Rice PA."],"DOI_URL":"https://doi.org/10.1038/nsmb.3286"}},"set_info":{"accession":"CL0023","name":"P-loop_NTPase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":36,"interactions":0,"matches":1976,"pathways":0,"proteins":1975,"proteomes":1538,"sets":1,"structural_models":{"alphafold":1279},"structures":2,"taxa":2869},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":14,"alignment:full":826},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}