{"metadata":{"accession":"PF06037","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010321","hierarchy":null,"name":{"name":"Bacterial protein of unknown function (DUF922)","short":"DUF922"},"description":[{"text":"<p>This family of proteins has a conserved HEXXH motif, suggesting they are putative peptidases of zincin fold [[cite:PUB00075429]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00075429":{"PMID":23671590,"ISBN":null,"volume":"8","issue":"5","year":2013,"title":"CLCAs - a family of metalloproteases of intriguing phylogenetic distribution and with cases of substituted catalytic sites.","URL":null,"raw_pages":"e62272","medline_journal":"PLoS One","ISO_journal":"PLoS ONE","authors":["Lenart A","Dudkiewicz M","Grynberg M","Pawlowski K."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pone.0062272"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":7,"interactions":0,"matches":2332,"pathways":0,"proteins":2324,"proteomes":1709,"sets":0,"structural_models":{"alphafold":1423},"structures":0,"taxa":2478},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":259,"alignment:full":1007},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}