{"metadata":{"accession":"PF06023","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR009260","hierarchy":null,"name":{"name":"CRISPR-associated exonuclease Csa1","short":"Csa1"},"description":[{"text":"<p>CRISPR (clustered regularly interspaced short palindromic repeats) elements and cas (CRISPR-associated) genes are widespread in Bacteria and Archaea. The CRISPR/Cas system operates as a defense mechanism against mobile genetic elements (i.e., viruses or plasmids). Csa1 is part of the archaeal subtype I-A system. Cas1 has not yet been enzymatically characterised [[cite:PUB00073621]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00073621":{"PMID":22408157,"ISBN":null,"volume":"194","issue":"10","year":2012,"title":"Characterization of the CRISPR/Cas subtype I-A system of the hyperthermophilic crenarchaeon Thermoproteus tenax.","URL":null,"raw_pages":"2491-500","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Plagens A","Tjaden B","Hagemann A","Randau L","Hensel R."],"DOI_URL":"http://dx.doi.org/10.1128/JB.00206-12"}},"set_info":{"accession":"CL0236","name":"PDDEXK"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":120,"pathways":0,"proteins":114,"proteomes":90,"sets":1,"structural_models":{"alphafold":111},"structures":0,"taxa":257},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":7,"alignment:full":74},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}