{"metadata":{"accession":"PF06011","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010308","hierarchy":null,"name":{"name":"Transient receptor potential (TRP) ion channel","short":"TRP"},"description":[{"text":"<p>This family of proteins are transient receptor potential (TRP) ion channels.              They are essential for cellular viability and are involved in cell growth and cell wall synthesis [[cite:PUB00020495]].  The genes for these proteins are homologous to polycystic kidney disease related ion channel genes [[cite:PUB00020495]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"TRPV","extract":"<p><b>TRPV</b> is a family of transient receptor potential cation channels in animals. All TRPVs are highly calcium selective.</p>","thumbnail":null}],"literature":{"PUB00020495":{"PMID":15537393,"ISBN":null,"volume":"387","issue":"Pt 1","year":2005,"title":"A microbial TRP-like polycystic-kidney-disease-related ion channel gene.","URL":null,"raw_pages":"211-9","medline_journal":"Biochem J","ISO_journal":"Biochem. J.","authors":["Palmer CP","Aydar E","Djamgoz MB."],"DOI_URL":"http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=15537393&action=stream&blobtype=pdf"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":136,"interactions":0,"matches":5855,"pathways":0,"proteins":5709,"proteomes":1551,"sets":0,"structural_models":{"alphafold":4511},"structures":0,"taxa":3364},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":189,"alignment:full":4685},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}