{"metadata":{"accession":"PF05991","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010298","hierarchy":null,"name":{"name":"YacP-like NYN domain","short":"NYN_YacP"},"description":[{"text":"<p>This family consists of bacterial proteins related to YacP. This family is uncharacterised functionally, but it has been suggested that these proteins are nucleases due to them containing a NYN domain. NYN (for N4BP1, YacP-like Nuclease) domains were discovered by Anantharaman and Aravind [[cite:PUB00056584]].  Based on gene neighborhoods it was suggested that the bacterial YacP proteins interact with the Ribonuclease III and TrmH methylase in a processome complex that catalyzes the maturation of rRNA and tRNA [[cite:PUB00056584]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00056584":{"PMID":17114934,"ISBN":null,"volume":"3","issue":"1","year":2006,"title":"The NYN domains: novel predicted RNAses with a PIN domain-like fold.","URL":null,"raw_pages":"18-27","medline_journal":"RNA Biol","ISO_journal":"RNA Biol","authors":["Anantharaman V","Aravind L."],"DOI_URL":null}},"set_info":{"accession":"CL0280","name":"PIN"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":33,"interactions":0,"matches":6405,"pathways":0,"proteins":6344,"proteomes":5929,"sets":1,"structural_models":{"alphafold":4095},"structures":2,"taxa":9190},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":38,"alignment:full":3536},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}