{"metadata":{"accession":"PF05949","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010273","hierarchy":null,"name":{"name":"Bacterial protein of unknown function (DUF881)","short":"DUF881"},"description":[{"text":"<p>This family consists of a series of hypothetical bacterial proteins. One of the family members [swissprot:Q45543] from Bacillus subtilis is thought to be involved in cell division and sporulation [[cite:PUB00011928]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00011928":{"PMID":2556375,"ISBN":null,"volume":"171","issue":"12","year":1989,"title":"Nucleotide sequence and insertional inactivation of a Bacillus subtilis gene that affects cell division, sporulation, and temperature sensitivity.","URL":null,"raw_pages":"6821-34","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Beall B","Lutkenhaus J."],"DOI_URL":"http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=2556375"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":8826,"pathways":0,"proteins":8824,"proteomes":3335,"sets":0,"structural_models":{"alphafold":5317},"structures":1,"taxa":4412},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":222,"alignment:full":4594},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3gmg","name":"Crystal structure of an uncharacterized conserved protein from Mycobacterium tuberculosis"}}}