{"metadata":{"accession":"PF05303","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007967","hierarchy":null,"name":{"name":"GSKIP domain","short":"GSKIP_dom"},"description":[{"text":"<p>This domain is found in GSK3-beta interaction protein (GSKIP), which binds to GSK3beta [[cite:PUB00054079]]. It is also found as a short domain towards the N terminus in clustered mitochondria protein, also known as clueless in Drosophila, which is involved in proper cytoplasmic distribution of mitochondria [[cite:PUB00064791],[cite:PUB00068099],[cite:PUB00068100]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00068099":{"PMID":14617080,"ISBN":null,"volume":"36","issue":"4","year":2003,"title":"The genetic control of plant mitochondrial morphology and dynamics.","URL":null,"raw_pages":"500-9","medline_journal":"Plant J","ISO_journal":"Plant J.","authors":["Logan DC","Scott I","Tobin AK."],"DOI_URL":"http://dx.doi.org/10.1046/j.1365-313X.2003.01894.x"},"PUB00064791":{"PMID":19638420,"ISBN":null,"volume":"2","issue":"9-10","year":2009,"title":"Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin.","URL":null,"raw_pages":"490-9","medline_journal":"Dis Model Mech","ISO_journal":"Dis Model Mech","authors":["Cox RT","Spradling AC."],"DOI_URL":null},"PUB00068100":{"PMID":9601101,"ISBN":null,"volume":"111 ( Pt 12)","issue":null,"year":1998,"title":"The S. cerevisiae CLU1 and D. discoideum cluA genes are functional homologues that influence mitochondrial morphology and distribution.","URL":null,"raw_pages":"1717-27","medline_journal":"J Cell Sci","ISO_journal":"J. Cell. Sci.","authors":["Fields SD","Conrad MN","Clarke M."],"DOI_URL":null},"PUB00054079":{"PMID":16981698,"ISBN":null,"volume":"45","issue":"38","year":2006,"title":"GSKIP is homologous to the Axin GSK3beta interaction domain and functions as a negative regulator of GSK3beta.","URL":null,"raw_pages":"11379-89","medline_journal":"Biochemistry","ISO_journal":"Biochemistry","authors":["Chou HY","Howng SL","Cheng TS","Hsiao YL","Lieu AS","Loh JK","Hwang SL","Lin CC","Hsu CM","Wang C","Lee CI","Lu PJ","Chou CK","Huang CY","Hong YR."],"DOI_URL":"http://dx.doi.org/10.1021/bi061147r"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":85,"interactions":0,"matches":3271,"pathways":0,"proteins":3265,"proteomes":2124,"sets":0,"structural_models":{"alphafold":2130},"structures":1,"taxa":6349},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":23,"alignment:full":2456},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}