{"metadata":{"accession":"PF05301","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007965","hierarchy":null,"name":{"name":"GNAT acetyltransferase, Mec-17","short":"Acetyltransf_16"},"description":[{"text":"<p>Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor [[cite:PUB00053857]]. The family shares all the residue-motifs characteristic of Gcn5-related acetyl-transferases, though the exact unction is still unknown [[cite:PUB00044970]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044970":{"PMID":17172875,"ISBN":null,"volume":"5","issue":"24","year":2006,"title":"Eukaryotic domain of unknown function DUF738 belongs to Gcn5-related N-acetyltransferase superfamily.","URL":null,"raw_pages":"2927-30","medline_journal":"Cell Cycle","ISO_journal":"Cell Cycle","authors":["Steczkiewicz K","Kinch L","Grishin NV","Rychlewski L","Ginalski K."],"DOI_URL":null},"PUB00053857":{"PMID":12124626,"ISBN":null,"volume":"418","issue":"6895","year":2002,"title":"Identification of genes expressed in C. elegans touch receptor neurons.","URL":null,"raw_pages":"331-5","medline_journal":"Nature","ISO_journal":"Nature","authors":["Zhang Y","Ma C","Delohery T","Nasipak B","Foat BC","Bounoutas A","Bussemaker HJ","Kim SK","Chalfie M."],"DOI_URL":"http://dx.doi.org/10.1038/nature00891"}},"set_info":{"accession":"CL0257","name":"Acetyltrans"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":22,"interactions":0,"matches":2415,"pathways":0,"proteins":2356,"proteomes":1155,"sets":1,"structural_models":{"alphafold":2052},"structures":18,"taxa":3938},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":28,"alignment:full":1842},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4pk3","name":"tubulin acetyltransferase complex with bisubstrate analog"}}}