{"metadata":{"accession":"PF04950","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007034","hierarchy":null,"name":{"name":"40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal","short":"RIBIOP_C"},"description":[{"text":"<p>RIBIOP_C is a family of eukaryotic proteins from the C-terminus of pre-rRNA-processing protein or ribosome biogenesis proteins BMS1 and TSR1. These proteins act, in the nucleolus, as a molecular switch during maturation of the 40S ribosomal subunit [[cite:PUB00072548],[cite:PUB00072547]]. This domain, domain IV of translation elongation factor selb, adopts the same fold as translation proteins such as domain II of GTP-elongation factor Tu proteins [[cite:PUB00038060]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00038060":{"PMID":15616587,"ISBN":null,"volume":"24","issue":"1","year":2005,"title":"Selenocysteine tRNA-specific elongation factor SelB is a structural chimaera of elongation and initiation factors.","URL":null,"raw_pages":"11-22","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Leibundgut M","Frick C","Thanbichler M","Bock A","Ban N."],"DOI_URL":"http://dx.doi.org/10.1038/sj.emboj.7600505"},"PUB00072547":{"PMID":11565748,"ISBN":null,"volume":"7","issue":"9","year":2001,"title":"Bms1p, a G-domain-containing protein, associates with Rcl1p and is required for 18S rRNA biogenesis in yeast.","URL":null,"raw_pages":"1254-67","medline_journal":"RNA","ISO_journal":"RNA","authors":["Wegierski T","Billy E","Nasr F","Filipowicz W."],"DOI_URL":"http://dx.doi.org/10.1017/S1355838201012079"},"PUB00072548":{"PMID":11565749,"ISBN":null,"volume":"7","issue":"9","year":2001,"title":"Bms1p, a novel GTP-binding protein, and the related Tsr1p are required for distinct steps of 40S ribosome biogenesis in yeast.","URL":null,"raw_pages":"1268-83","medline_journal":"RNA","ISO_journal":"RNA","authors":["Gelperin D","Horton L","Beckman J","Hensold J","Lemmon SK."],"DOI_URL":"http://dx.doi.org/10.1017/S1355838201013073"}},"set_info":{"accession":"CL0866","name":"ALR_C-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":164,"interactions":0,"matches":8930,"pathways":0,"proteins":8669,"proteomes":3455,"sets":1,"structural_models":{"alphafold":6899},"structures":84,"taxa":9157},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":174,"alignment:full":6857},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}