{"metadata":{"accession":"PF04939","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007023","hierarchy":null,"name":{"name":"Ribosome biogenesis regulatory protein (RRS1)","short":"RRS1"},"description":[{"text":"<p>This family consists of several eukaryotic ribosome biogenesis regulatory (RRS1) proteins. RRS1 is a nuclear protein that is essential for the maturation of 25 S rRNA and the 60 S ribosomal subunit assembly in Saccharomyces cerevisiae [[cite:PUB00020277]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00020277":{"PMID":12048200,"ISBN":null,"volume":"277","issue":"32","year":2002,"title":"Rpf2p, an evolutionarily conserved protein, interacts with ribosomal protein L11 and is essential for the processing of 27 SB Pre-rRNA to 25 S rRNA and the 60 S ribosomal subunit assembly in Saccharomyces cerevisiae.","URL":null,"raw_pages":"28780-6","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Morita D","Miyoshi K","Matsui Y","Toh-E A","Shinkawa H","Miyakawa T","Mizuta K."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M203399200"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":66,"interactions":0,"matches":3721,"pathways":0,"proteins":3691,"proteomes":3104,"sets":0,"structural_models":{"alphafold":3129},"structures":42,"taxa":8264},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":135,"alignment:full":2768},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5wxl","name":"Crystal structure of the Rrs1 and Rpf2 complex"}}}