{"metadata":{"accession":"PF04910","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR006994","hierarchy":null,"name":{"name":"Transcriptional repressor TCF25","short":"Tcf25"},"description":[{"text":"<p>Members of this family are transcriptional repressors. They may act by increasing histone deacetylase activity at promoter regions [[cite:PUB00033388]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00033388":{"PMID":16574069,"ISBN":null,"volume":"343","issue":"3","year":2006,"title":"hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor.","URL":null,"raw_pages":"973-81","medline_journal":"Biochem Biophys Res Commun","ISO_journal":"Biochem. Biophys. Res. Commun.","authors":["Cai Z","Wang Y","Yu W","Xiao J","Li Y","Liu L","Zhu C","Tan K","Deng Y","Yuan W","Liu M","Wu X."],"DOI_URL":null}},"set_info":{"accession":"CL0020","name":"TPR"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":77,"interactions":0,"matches":4442,"pathways":0,"proteins":4322,"proteomes":3288,"sets":1,"structural_models":{"alphafold":3667},"structures":1,"taxa":8736},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":74,"alignment:full":3389},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}