{"metadata":{"accession":"PF04828","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR006913","hierarchy":null,"name":{"name":"Glutathione-dependent formaldehyde-activating enzyme","short":"GFA"},"description":[{"text":"<p>The GFA enzyme catalyzes the first step in the detoxification of formaldehyde. This domain has a beta-tent fold [[cite:PUB00078711]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00078711":{"PMID":25569776,"ISBN":null,"volume":"11","issue":"1","year":2015,"title":"The thalidomide-binding domain of cereblon defines the CULT domain family and is a new member of the β-tent fold.","URL":null,"raw_pages":"e1004023","medline_journal":"PLoS Comput Biol","ISO_journal":"PLoS Comput. Biol.","authors":["Lupas AN","Zhu H","Korycinski M."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pcbi.1004023"}},"set_info":{"accession":"CL0080","name":"Beta-tent"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":268,"interactions":0,"matches":39383,"pathways":0,"proteins":38163,"proteomes":8672,"sets":1,"structural_models":{"alphafold":26902},"structures":4,"taxa":15338},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":28,"alignment:full":23939},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"8ajq","name":"Crystal structure of PA2722 from Pseudomonas aeruginosa PAO1"}}}