{"metadata":{"accession":"PF04783","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR006868","hierarchy":null,"name":{"name":"Protein of unknown function (DUF630)","short":"DUF630"},"description":[{"text":"<p>This region is sometimes found at the N-terminus of putative plant bZIP proteins.  Its function is not known. Structural modelling suggests this domain may bind nucleic acids [[cite:PUB00070793]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00070793":{"PMID":21348639,"ISBN":null,"volume":"15","issue":"7-8","year":2011,"title":"Ab initio modeling led annotation suggests nucleic acid binding function for many DUFs.","URL":null,"raw_pages":"431-8","medline_journal":"OMICS","ISO_journal":"OMICS","authors":["Rigden DJ."],"DOI_URL":"http://dx.doi.org/10.1089/omi.2010.0122"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":88,"interactions":0,"matches":7424,"pathways":0,"proteins":7419,"proteomes":379,"sets":0,"structural_models":{"alphafold":6024},"structures":0,"taxa":1076},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":76,"alignment:full":4668},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}