{"metadata":{"accession":"PF04525","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007612","hierarchy":null,"name":{"name":"LURP-one-related","short":"LOR"},"description":[{"text":"<p>The structure of this family has been solved. It comprises a 12-stranded beta barrel with a central C-terminal alpha helix. This helix is thought to be a transmembrane helix. It is structurally similar to the C-terminal domain of the Tubby protein [[cite:PUB00057493]]. In plants it plays a role in defense against pathogens [[cite:PUB00057494]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057494":{"PMID":18346188,"ISBN":null,"volume":"55","issue":"1","year":2008,"title":"The oomycete response gene LURP1 is required for defense against Hyaloperonospora parasitica in Arabidopsis thaliana.","URL":null,"raw_pages":"53-64","medline_journal":"Plant J","ISO_journal":"Plant J.","authors":["Knoth C","Eulgem T."],"DOI_URL":"http://dx.doi.org/10.1111/j.1365-313X.2008.03486.x"},"PUB00057493":{"PMID":19010806,"ISBN":null,"volume":"25","issue":"2","year":2009,"title":"Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane tethered transcription factors.","URL":null,"raw_pages":"159-62","medline_journal":"Bioinformatics","ISO_journal":"Bioinformatics","authors":["Bateman A","Finn RD","Sims PJ","Wiedmer T","Biegert A","Soding J."],"DOI_URL":"http://dx.doi.org/10.1093/bioinformatics/btn595"}},"set_info":{"accession":"CL0395","name":"Tubby_C"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":130,"interactions":0,"matches":15178,"pathways":0,"proteins":14951,"proteomes":4601,"sets":1,"structural_models":{"alphafold":11500},"structures":2,"taxa":7829},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":358,"alignment:full":9536},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2q4m","name":"Ensemble refinement of the crystal structure of protein from Arabidopsis thaliana At5g01750"}}}