{"metadata":{"accession":"PF04445","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007536","hierarchy":null,"name":{"name":"Putative SAM-dependent methyltransferase","short":"SAM_MT"},"description":[{"text":"<p>This is a family of putative SAM-dependent methyltransferases.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00010005":{"PMID":10629202,"ISBN":null,"volume":"182","issue":"2","year":2000,"title":"opdA, a Salmonella enterica serovar Typhimurium gene encoding a protease, is part of an operon regulated by heat shock.","URL":null,"raw_pages":"518-21","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Conlin CA","Miller CG."],"DOI_URL":"http://dx.doi.org/10.1128/JB.182.2.518-521.2000"}},"set_info":{"accession":"CL0063","name":"NADP_Rossmann"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":10,"interactions":0,"matches":4516,"pathways":0,"proteins":4503,"proteomes":4361,"sets":1,"structural_models":{"alphafold":2856},"structures":4,"taxa":6310},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":28,"alignment:full":1858},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2pgx","name":"Crystal structure of UPF0341 protein yhiQ from E. coli, Northeast Structural Genomics Target ER585"}}}