{"metadata":{"accession":"PF04368","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007463","hierarchy":null,"name":{"name":"Protein of unknown function (DUF507)","short":"DUF507"},"description":[{"text":"<p>This entry represents a bacterial domain with an unknown function. It folds into a Y-shaped alpha-helical structure, comprising an anti- parallel 4-helix bundle at the base and two helical arms [[cite:PUB00153915]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00153915":{"PMID":37596303,"ISBN":null,"volume":"13","issue":"1","year":2023,"title":"Crystal structure of domain of unknown function 507 (DUF507) reveals a new protein fold.","URL":null,"raw_pages":"13496","medline_journal":"Sci Rep","ISO_journal":"Sci Rep","authors":["McKay CE","Cheng J","Tanner JJ."],"DOI_URL":"https://doi.org/10.1038/s41598-023-40558-y"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":480,"pathways":0,"proteins":480,"proteomes":381,"sets":0,"structural_models":{"alphafold":357},"structures":2,"taxa":694},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":285},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"8t8k","name":"Structure of Domain of Unknown Function 507 (DUF507) in Space Group C222(1)"}}}