{"metadata":{"accession":"PF04327","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007422","hierarchy":null,"name":{"name":"Cysteine protease Prp","short":"Peptidase_Prp"},"description":[{"text":"<p>This is a family of cysteine protease that are found to cleave the N-terminus extension of ribosomal subunit L27 in eubacteria. Proteins in this family are distinguished by a pair of invariant histidine and cysteine residues with conserved spacing that form the classic catalytic dyad of a cysteine protease [[cite:PUB00075697]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00075697":{"PMID":25388641,"ISBN":null,"volume":"95","issue":"2","year":2015,"title":"Specific N-terminal cleavage of ribosomal protein L27 in Staphylococcus aureus and related bacteria.","URL":null,"raw_pages":"258-69","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Wall EA","Caufield JH","Lyons CE","Manning KA","Dokland T","Christie GE."],"DOI_URL":"http://dx.doi.org/10.1111/mmi.12862"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":3437,"pathways":0,"proteins":3437,"proteomes":3303,"sets":0,"structural_models":{"alphafold":2293},"structures":7,"taxa":4959},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":157,"alignment:full":1845},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4peo","name":"Crystal structure of a hypothetical protein from Staphylococcus aureus."}}}