{"metadata":{"accession":"PF04301","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007398","hierarchy":null,"name":{"name":"Pimeloyl-ACP methyl esterase BioG","short":"BioG"},"description":[{"text":"<p>This protein family includes Pimeloyl-ACP methyl esterase BioG from Haemophilus influenzae ([swissprot:P44251]) and similar bacterial proteins. This enzyme is involved in the biosynthesis of pymeloyl-ACP and, hence, in biotin biosynthesis. It is organised into a a core domain formed by a seven-stranded beta-sheet and a lid domain consisting of four alpha-helices [[cite:PUB00100663]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00100663":{"PMID":27933801,"ISBN":null,"volume":"55","issue":"48","year":2016,"title":"An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus influenzae.","URL":null,"raw_pages":"6705-6717","medline_journal":"Biochemistry","ISO_journal":"Biochemistry","authors":["Shi J","Cao X","Chen Y","Cronan JE","Guo Z."],"DOI_URL":null}},"set_info":{"accession":"CL0028","name":"AB_hydrolase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":461,"pathways":0,"proteins":460,"proteomes":457,"sets":1,"structural_models":{"alphafold":323},"structures":2,"taxa":821},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":250},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5gng","name":"Crystal Structure of BioG from Haemophilus influenzae at 1.26 Angstroms resolution"}}}