{"metadata":{"accession":"PF04266","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007374","hierarchy":null,"name":{"name":"ASCH domain","short":"ASCH"},"description":[{"text":"<p>The ASCH domain adopts a beta-barrel fold similar to the [pfam:PF01472] domain [[cite:PUB00044668]]. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation [[cite:PUB00044668]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00044668":{"PMID":16322048,"ISBN":null,"volume":"22","issue":"3","year":2006,"title":"The ASCH superfamily: novel domains with a fold related to the PUA domain and a potential role in RNA metabolism.","URL":null,"raw_pages":"257-63","medline_journal":"Bioinformatics","ISO_journal":"Bioinformatics","authors":["Iyer LM","Burroughs AM","Aravind L."],"DOI_URL":"http://dx.doi.org/10.1093/bioinformatics/bti767"}},"set_info":{"accession":"CL0178","name":"PUA"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":96,"interactions":0,"matches":5494,"pathways":0,"proteins":5492,"proteomes":3650,"sets":1,"structural_models":{"alphafold":4036},"structures":19,"taxa":9046},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":33,"alignment:full":3369},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2z0t","name":"Crystal structure of hypothetical protein PH0355"}}}