{"metadata":{"accession":"PF04229","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007344","hierarchy":null,"name":{"name":"GrpB protein","short":"GrpB"},"description":[{"text":"<p>This family has been suggested to belong to the nucleotidyltransferase superfamily [[cite:PUB00066751]].  It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme [[cite:PUB00066752]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00066751":{"PMID":19833706,"ISBN":null,"volume":"37","issue":"22","year":2009,"title":"Comprehensive classification of nucleotidyltransferase fold proteins: identification of novel families and their representatives in human.","URL":null,"raw_pages":"7701-14","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Kuchta K","Knizewski L","Wyrwicz LS","Rychlewski L","Ginalski K."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gkp854"},"PUB00066752":{"PMID":19876400,"ISBN":null,"volume":"4","issue":"10","year":2009,"title":"The role of UPF0157 in the folding of M. tuberculosis dephosphocoenzyme A kinase and the regulation of the latter by CTP.","URL":null,"raw_pages":"e7645","medline_journal":"PLoS One","ISO_journal":"PLoS ONE","authors":["Walia G","Kumar P","Surolia A."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pone.0007645"}},"set_info":{"accession":"CL0260","name":"NTP_transf"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":98,"interactions":0,"matches":7971,"pathways":0,"proteins":7942,"proteomes":5605,"sets":1,"structural_models":{"alphafold":4945},"structures":2,"taxa":8694},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":191,"alignment:full":3923},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2nrk","name":"Crystal structure of conserved protein GrpB from Enterococcus faecalis"}}}