{"metadata":{"accession":"PF04134","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007263","hierarchy":null,"name":{"name":"DCC1-like thiol-disulfide oxidoreductase","short":"DCC1-like"},"description":[{"text":"<p>Members of this family have two highly conserved cysteine residues within the DxxCxxC motif at the N-terminal. This motif is conserved in the thiol-disulfide oxidoreductase family [[cite:PUB00096851]]. This family includes At5g50100 (also known as DCC1) from Arabidopsis thaliana, a thioredoxin that modulates ROS homeostasis resulting in de novo shoot initiation and may be involved in the improvement of the capacity of plant regeneration [[cite:PUB00096851]]. Uncharacterised proteins from bacteria are also included in this family.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00096851":{"PMID":28724620,"ISBN":null,"volume":"176","issue":"3","year":2018,"title":"Thioredoxin-Mediated ROS Homeostasis Explains Natural Variation in Plant Regeneration.","URL":null,"raw_pages":"2231-2250","medline_journal":"Plant Physiol","ISO_journal":"Plant Physiol","authors":["Zhang H","Zhang TT","Liu H","Shi Y","Wang M","Bie XM","Li XG","Zhang XS."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":78,"interactions":0,"matches":12712,"pathways":0,"proteins":12691,"proteomes":9253,"sets":0,"structural_models":{"alphafold":8314},"structures":0,"taxa":14036},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":65,"alignment:full":6373},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}