{"metadata":{"accession":"PF04041","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007184","hierarchy":null,"name":{"name":"beta-1,4-mannooligosaccharide phosphorylase","short":"Glyco_hydro_130"},"description":[{"text":"<p>This is a family of glycosyl-hydrolases of the CAZy GH130 family. Several have been characterised as mannosylglucose phosphorylase [[cite:PUB00068792],[cite:PUB00068791],[cite:PUB00109137]]. This enzyme is part of the mannan catalytic pathway and feeds into the glycolysis cycle [[cite:PUB00068792]]. Specifically it catalyses the reversible phosphorolysis of beta-1,4-D-mannosyl-N-acetyl-D-glucosamine [[cite:PUB00109137]]. This family was noted to belong to the Beta fructosidase superfamily in [[cite:PUB00015849]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00068792":{"PMID":21539815,"ISBN":null,"volume":"408","issue":"4","year":2011,"title":"New microbial mannan catabolic pathway that involves a novel mannosylglucose phosphorylase.","URL":null,"raw_pages":"701-6","medline_journal":"Biochem Biophys Res Commun","ISO_journal":"Biochem. Biophys. Res. Commun.","authors":["Senoura T","Ito S","Taguchi H","Higa M","Hamada S","Matsui H","Ozawa T","Jin S","Watanabe J","Wasaki J","Ito S."],"DOI_URL":"http://dx.doi.org/10.1016/j.bbrc.2011.04.095"},"PUB00068791":{"PMID":23093406,"ISBN":null,"volume":"287","issue":"50","year":2012,"title":"Metabolic mechanism of mannan in a ruminal bacterium, Ruminococcus albus, involving two mannoside phosphorylases and cellobiose 2-epimerase: discovery of a new carbohydrate phosphorylase, β-1,4-mannooligosaccharide phosphorylase.","URL":null,"raw_pages":"42389-99","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Kawahara R","Saburi W","Odaka R","Taguchi H","Ito S","Mori H","Matsui H."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M112.390336"},"PUB00015849":{"PMID":11093261,"ISBN":null,"volume":"42","issue":"1","year":2001,"title":"beta-fructosidase superfamily: homology with some alpha-L-arabinases and beta-D-xylosidases.","URL":null,"raw_pages":"66-76","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Naumoff DG."],"DOI_URL":"http://dx.doi.org/10.1002/1097-0134(20010101)42:1<66::AID-PROT70>3.0.CO;2-4"},"PUB00109137":{"PMID":23943617,"ISBN":null,"volume":"288","issue":"38","year":2013,"title":"Discovery of β-1,4-D-mannosyl-N-acetyl-D-glucosamine phosphorylase involved in the metabolism of N-glycans.","URL":null,"raw_pages":"27366-27374","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Nihira T","Suzuki E","Kitaoka M","Nishimoto M","Ohtsubo K","Nakai H."],"DOI_URL":null}},"set_info":{"accession":"CL0143","name":"B_Fructosidase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":27,"interactions":0,"matches":6975,"pathways":0,"proteins":6736,"proteomes":3640,"sets":1,"structural_models":{"alphafold":4505},"structures":33,"taxa":5878},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":3929},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4udg","name":"Crystal structure of b-1,4-mannopyranosyl-chitobiose phosphorylase at 1.60 Angstrom in complex with N-acetylglucosamine and inorganic phosphate"}}}