{"metadata":{"accession":"PF04019","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR007164","hierarchy":null,"name":{"name":"Protein of unknown function (DUF359)","short":"DUF359"},"description":[{"text":"<p>This family of archaebacterial proteins are about 170 amino acids in length.  They have no known function. The most conserved portion of the protein contains the sequence GEEDL that may be important for its function.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":624,"pathways":0,"proteins":624,"proteomes":609,"sets":0,"structural_models":{"alphafold":586},"structures":3,"taxa":1110},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":70,"alignment:full":304},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}