{"metadata":{"accession":"PF04010","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR023140","hierarchy":null,"name":{"name":"Protein of unknown function (DUF357)","short":"DUF357"},"description":[{"text":"<p>Members of this family are short (less than 100 amino acid) proteins found in archaebacteria.  The function of these proteins is unknown.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":639,"pathways":0,"proteins":608,"proteomes":602,"sets":0,"structural_models":{"alphafold":574},"structures":4,"taxa":1088},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":51,"alignment:full":318},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"4fzp","name":"Crystal Structure of the uranyl binding protein complexed with uranyl"}}}