{"metadata":{"accession":"PF03660","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR005345","hierarchy":null,"name":{"name":"PHF5-like protein","short":"PHF5"},"description":[{"text":"<p>This family of proteins the superfamily of PHD-finger proteins. At least one example, from mouse, may act as a chromatin-associated protein[[cite:PUB00020105]]. The S. pombe ini1 gene is essential, required for splicing [[cite:PUB00020106]]. It is localised in the nucleus, but not detected in the nucleolus and can be complemented by human ini1 [[cite:PUB00020106]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00020106":{"PMID":14762117,"ISBN":null,"volume":"117","issue":"Pt 6","year":2004,"title":"A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast.","URL":null,"raw_pages":"967-74","medline_journal":"J Cell Sci","ISO_journal":"J. Cell. Sci.","authors":["Oltra E","Verde F","Werner R","D'Urso G."],"DOI_URL":"http://dx.doi.org/10.1242/jcs.00946"},"PUB00020105":{"PMID":12054543,"ISBN":null,"volume":"293","issue":"2","year":2002,"title":"Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif.","URL":null,"raw_pages":"816-26","medline_journal":"Biochem Biophys Res Commun","ISO_journal":"Biochem. Biophys. Res. Commun.","authors":["Trappe R","Ahmed M","Glaser B","Vogel C","Tascou S","Burfeind P","Engel W."],"DOI_URL":"http://dx.doi.org/10.1016/S0006-291X(02)00277-2"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":72,"interactions":0,"matches":3792,"pathways":0,"proteins":3763,"proteomes":3034,"sets":0,"structural_models":{"alphafold":3231},"structures":75,"taxa":8299},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":36,"alignment:full":2885},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5syb","name":"Crystal structure of human PHF5A"}}}