{"metadata":{"accession":"PF03619","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR005178","hierarchy":null,"name":{"name":"Organic solute transporter Ostalpha","short":"Solute_trans_a"},"description":[{"text":"<p>This family is a transmembrane organic solute transport protein. In vertebrates these proteins form a complex with Ostbeta, and function as bile transporters [[cite:PUB00057471]]. In plants they may transport brassinosteroid-like compounds and act as regulators of cell death [[cite:PUB00057472]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057471":{"PMID":15563450,"ISBN":null,"volume":"280","issue":"8","year":2005,"title":"The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter.","URL":null,"raw_pages":"6960-8","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Dawson PA","Hubbert M","Haywood J","Craddock AL","Zerangue N","Christian WV","Ballatori N."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M412752200"},"PUB00057472":{"PMID":20830211,"ISBN":null,"volume":"5","issue":"9","year":2010,"title":"Lazarus1, a DUF300 protein, contributes to programmed cell death associated with Arabidopsis acd11 and the hypersensitive response.","URL":null,"raw_pages":"e12586","medline_journal":"PLoS One","ISO_journal":"PLoS ONE","authors":["Malinovsky FG","Brodersen P","Fiil BK","McKinney LV","Thorgrimsen S","Beck M","Nielsen HB","Pietra S","Zipfel C","Robatzek S","Petersen M","Hofius D","Mundy J."],"DOI_URL":"http://dx.doi.org/10.1371/journal.pone.0012586"}},"set_info":{"accession":"CL0192","name":"GPCR_A"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":210,"interactions":0,"matches":16888,"pathways":0,"proteins":16376,"proteomes":3347,"sets":1,"structural_models":{"alphafold":14134},"structures":10,"taxa":8907},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":252,"alignment:full":12832},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}