{"metadata":{"accession":"PF03401","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR005064","hierarchy":null,"name":{"name":"Tripartite tricarboxylate transporter family receptor","short":"TctC"},"description":[{"text":"<p>These probable extra-cytoplasmic solute receptors are strongly overrepresented in several beta-proteobacteria [[cite:PUB00019234]].  This family, formerly known as Bug - Bordetella uptake gene (bug) product - is a family of bacterial tripartite tricarboxylate receptors of the extracytoplasmic solute binding receptor-dependent transporter group of families, distinct from the ABC and TRAP-T families [[cite:PUB00106922]]. The TctABC system has been characterised in S. typhimurium [[cite:PUB00106923]], and TctC is the extracytoplasmic tricarboxylate-binding receptor which binds the transporters TctA and TctB, two integral membrane proteins. Complete three-component systems are found only in bacteria [[cite:PUB00106923]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00106922":{"PMID":6141166,"ISBN":null,"volume":"259","issue":"3","year":1984,"title":"Tricarboxylate-binding proteins of Salmonella typhimurium. Purification, crystallization, and physical properties.","URL":null,"raw_pages":"1586-92","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Sweet GD","Kay CM","Kay WW."],"DOI_URL":null},"PUB00019234":{"PMID":12562821,"ISBN":null,"volume":"185","issue":"4","year":2003,"title":"Overrepresentation of a gene family encoding extracytoplasmic solute receptors in Bordetella.","URL":null,"raw_pages":"1470-4","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Antoine R","Jacob-Dubuisson F","Drobecq H","Willery E","Lesjean S","Locht C."],"DOI_URL":"http://dx.doi.org/10.1128/JB.185.4.1470-1474.2003"},"PUB00106923":{"PMID":14499931,"ISBN":null,"volume":"154","issue":"7","year":2003,"title":"The tripartite tricarboxylate transporter (TTT) family.","URL":null,"raw_pages":"457-65","medline_journal":"Res Microbiol","ISO_journal":"Res Microbiol","authors":["Winnen B","Hvorup RN","Saier MH Jr."],"DOI_URL":null}},"set_info":{"accession":"CL0177","name":"PBP"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":60,"interactions":0,"matches":64621,"pathways":0,"proteins":64590,"proteomes":6826,"sets":1,"structural_models":{"alphafold":38963},"structures":13,"taxa":9512},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":33481},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2qpq","name":"Structure of Bug27 from Bordetella pertussis"}}}