{"metadata":{"accession":"PF03237","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":null,"hierarchy":null,"name":{"name":"Terminase large subunit, T4likevirus-type, N-terminal","short":"Terminase_6N"},"description":[{"text":"<p>This entry represents the N-terminal domain of terminase large subunits found in a variety of the Caudovirales and prophage regions of bacterial genomes. It includes the terminase large subunit of Bacteriophage T4 (terminase gene 17, Gp17) [[cite:PUB00082635],[cite:PUB00095683]]. Homologues are also found in Gene Transfer Agents (GTA) [[cite:PUB00055430]], including ORFg2 (RCAP_rcc01683) of the GTA of Rhodobacter capsulatus (Rhodopseudomonas capsulata) [see Fig.1, in 4].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00095683":{"PMID":12466275,"ISBN":null,"volume":"278","issue":"7","year":2003,"title":"Isolation and characterization of T4 bacteriophage gp17 terminase, a large subunit multimer with enhanced ATPase activity.","URL":null,"raw_pages":"4618-27","medline_journal":"J Biol Chem","ISO_journal":"J Biol Chem","authors":["Baumann RG","Black LW."],"DOI_URL":null},"PUB00055430":{"PMID":11382219,"ISBN":null,"volume":"175","issue":"4","year":2001,"title":"The gene transfer agent of Rhodobacter capsulatus and \"constitutive transduction\" in prokaryotes.","URL":null,"raw_pages":"241-9","medline_journal":"Arch Microbiol","ISO_journal":"Arch. Microbiol.","authors":["Lang AS","Beatty JT."],"DOI_URL":"http://dx.doi.org/10.1007/s002030100260"},"PUB00082635":{"PMID":12235385,"ISBN":null,"volume":"30","issue":"18","year":2002,"title":"Sequence analysis of bacteriophage T4 DNA packaging/terminase genes 16 and 17 reveals a common ATPase center in the large subunit of viral terminases.","URL":null,"raw_pages":"4009-21","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Mitchell MS","Matsuzaki S","Imai S","Rao VB."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gkf524"},"PUB00055431":{"PMID":12399927,"ISBN":null,"volume":"55","issue":"5","year":2002,"title":"Evolutionary implications of phylogenetic analyses of the gene transfer agent (GTA) of Rhodobacter capsulatus.","URL":null,"raw_pages":"534-43","medline_journal":"J Mol Evol","ISO_journal":"J. Mol. Evol.","authors":["Lang AS","Taylor TA","Beatty JT."],"DOI_URL":"http://dx.doi.org/10.1007/s00239-002-2348-7"}},"set_info":{"accession":"CL0023","name":"P-loop_NTPase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":36,"interactions":0,"matches":8176,"pathways":0,"proteins":8175,"proteomes":6717,"sets":1,"structural_models":{"alphafold":3902},"structures":17,"taxa":12187},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":22,"alignment:full":4225},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"7ks4","name":"Thermus Phage P74-26 Large Terminase ATPase domain with partially bound ADP"}}}