{"metadata":{"accession":"PF03194","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR004882","hierarchy":null,"name":{"name":"LUC7 N_terminus","short":"LUC7"},"description":[{"text":"<p>This family contains the N terminal region of several LUC7 protein homologues and only contains eukaryotic proteins. LUC7 has been shown to be a U1 snRNA associated protein [[cite:PUB00016924]] with a role in splice site recognition [[cite:PUB00016923]]. The family also contains human and mouse LUC7 like (LUC7L) proteins [[cite:PUB00016922]] and human cisplatin resistance-associated overexpressed protein (CROP) [[cite:PUB00016921]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00016924":{"PMID":11804584,"ISBN":null,"volume":"9","issue":"1","year":2002,"title":"Composition and functional characterization of the yeast spliceosomal penta-snRNP.","URL":null,"raw_pages":"31-44","medline_journal":"Mol Cell","ISO_journal":"Mol. Cell","authors":["Stevens SW","Ryan DE","Ge HY","Moore RE","Young MK","Lee TD","Abelson J."],"DOI_URL":"http://dx.doi.org/10.1016/S1097-2765(02)00436-7"},"PUB00016923":{"PMID":10500099,"ISBN":null,"volume":"13","issue":"18","year":1999,"title":"Luc7p, a novel yeast U1 snRNP protein with a role in 5' splice site recognition.","URL":null,"raw_pages":"2425-38","medline_journal":"Genes Dev","ISO_journal":"Genes Dev.","authors":["Fortes P","Bilbao-Cortes D","Fornerod M","Rigaut G","Raymond W","Seraphin B","Mattaj IW."],"DOI_URL":"http://dx.doi.org/10.1101/gad.13.18.2425"},"PUB00016921":{"PMID":10631324,"ISBN":null,"volume":"465","issue":"2-3","year":2000,"title":"CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line.","URL":null,"raw_pages":"153-6","medline_journal":"FEBS Lett","ISO_journal":"FEBS Lett.","authors":["Nishii Y","Morishima M","Kakehi Y","Umehara K","Kioka N","Terano Y","Amachi T","Ueda K."],"DOI_URL":"http://dx.doi.org/10.1016/S0014-5793(99)01744-5"},"PUB00016922":{"PMID":11170747,"ISBN":null,"volume":"71","issue":"3","year":2001,"title":"Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain.","URL":null,"raw_pages":"307-14","medline_journal":"Genomics","ISO_journal":"Genomics","authors":["Tufarelli C","Frischauf AM","Hardison R","Flint J","Higgs DR."],"DOI_URL":"http://dx.doi.org/10.1006/geno.2000.6394"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":119,"interactions":0,"matches":10102,"pathways":0,"proteins":9105,"proteomes":3381,"sets":0,"structural_models":{"alphafold":7758},"structures":7,"taxa":8996},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":55,"alignment:full":7465},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}