{"metadata":{"accession":"PF03193","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR010914","hierarchy":null,"name":{"name":"RsgA GTPase","short":"RsgA_GTPase"},"description":[{"text":"<p>RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern [[cite:PUB00013951]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00013951":{"PMID":12220175,"ISBN":null,"volume":"41","issue":"37","year":2002,"title":"YjeQ, an essential, conserved, uncharacterized protein from Escherichia coli, is an unusual GTPase with circularly permuted G-motifs and marked burst kinetics.","URL":null,"raw_pages":"11109-17","medline_journal":"Biochemistry","ISO_journal":"Biochemistry","authors":["Daigle DM","Rossi L","Berghuis AM","Aravind L","Koonin EV","Brown ED."],"DOI_URL":"http://dx.doi.org/10.1021/bi020355q"}},"set_info":{"accession":"CL0023","name":"P-loop_NTPase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":40,"interactions":0,"matches":20432,"pathways":0,"proteins":20259,"proteomes":15648,"sets":1,"structural_models":{"alphafold":12792},"structures":17,"taxa":22637},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":58,"alignment:full":10288},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"2yv5","name":"Crystal structure of Yjeq from Aquifex aeolicus"}}}