{"metadata":{"accession":"PF03162","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR004861","hierarchy":null,"name":{"name":"Tyrosine phosphatase family","short":"Y_phosphatase2"},"description":[{"text":"<p>This family is closely related to the [pfam:PF00102] and [pfam:PF00782] families.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Protein_tyrosine_phosphatase","extract":"<p><b>Protein tyrosine phosphatases</b> (EC\t3.1.3.48, systematic name <b>protein-tyrosine-phosphate phosphohydrolase</b>) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins:</p><dl><dd>[a protein]-tyrosine phosphate + H<sub>2</sub>O = [a protein]-tyrosine + phosphate</dd></dl>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0031","name":"Phosphatase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":74,"interactions":0,"matches":6026,"pathways":0,"proteins":5842,"proteomes":2039,"sets":1,"structural_models":{"alphafold":4826},"structures":17,"taxa":4527},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":8,"alignment:full":4180},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"7mod","name":"Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in Complex with Phosphate in Conformation A (Pi(A))"}}}