{"metadata":{"accession":"PF03158","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR004858","hierarchy":null,"name":{"name":"Multigene family 530 protein","short":"DUF249"},"description":[{"text":"<p>Members of this family are multigene family 530 proteins from African swine fever viruses. These proteins may be involved in promoting survival of infected macrophages [[cite:PUB00007712]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00007712":{"PMID":11238833,"ISBN":null,"volume":"75","issue":"7","year":2001,"title":"African swine fever virus multigene family 360 and 530 genes are novel macrophage host range determinants.","URL":null,"raw_pages":"3066-76","medline_journal":"J Virol","ISO_journal":"J. Virol.","authors":["Zsak L","Lu Z","Burrage TG","Neilan JG","Kutish GF","Moore DM","Rock DL."],"DOI_URL":"http://dx.doi.org/10.1128/JVI.75.7.3066-3076.2001"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":158,"pathways":0,"proteins":158,"proteomes":17,"sets":0,"structural_models":{"alphafold":86},"structures":0,"taxa":26},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":8,"alignment:full":9},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}