Several members of this family are Borrelia burgdorferi plasmid proteins of uncharacterized function.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00019466":{"PMID":10672174,"ISBN":null,"volume":"35","issue":"3","year":2000,"title":"A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burgdorferi.","URL":null,"raw_pages":"490-516","medline_journal":"Mol Microbiol","ISO_journal":"Mol. Microbiol.","authors":["Casjens S","Palmer N","van Vugt R","Huang WM","Stevenson B","Rosa P","Lathigra R","Sutton G","Peterson J","Dodson RJ","Haft D","Hickey E","Gwinn M","White O","Fraser CM."],"DOI_URL":"http://dx.doi.org/10.1046/j.1365-2958.2000.01698.x"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":118,"pathways":0,"proteins":118,"proteomes":28,"sets":0,"structural_models":{"alphafold":78},"structures":0,"taxa":67},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":5,"alignment:full":15},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}