Members of this family are uncharacterised. They are 500-1200 amino acids in length and share a long region conservation that probably corresponds to several domains. The Go annotation for the protein indicates that it is involved in nematode larval development and has a positive regulation on growth rate.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0088","name":"Alk_phosphatase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":151,"interactions":0,"matches":6613,"pathways":0,"proteins":6003,"proteomes":653,"sets":1,"structural_models":{"alphafold":5153},"structures":0,"taxa":2252},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":17,"alignment:full":4777},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}