{"metadata":{"accession":"PF02713","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR003863","hierarchy":null,"name":{"name":"Domain of unknown function DUF220","short":"DUF220"},"description":[{"text":"<p>This is family consists of a region in several Arabidopsis thaliana hypothetical proteins none of which have any known function. The aligned region contains two cysteine residues. This domain shows structural similarity to members of the Bet v1-like superfamily [[cite:PUB00099734]] and may be involved in lipid binding.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00099734":{"PMID":31068459,"ISBN":null,"volume":"116","issue":"21","year":2019,"title":"JASSY, a chloroplast outer membrane protein required for jasmonate biosynthesis.","URL":null,"raw_pages":"10568-10575","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc Natl Acad Sci U S A","authors":["Guan L","Denkert N","Eisa A","Lehmann M","Sjuts I","Weiberg A","Soll J","Meinecke M","Schwenkert S."],"DOI_URL":null}},"set_info":{"accession":"CL0209","name":"Bet_v_1_like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":39,"interactions":0,"matches":1325,"pathways":0,"proteins":1251,"proteomes":409,"sets":1,"structural_models":{"alphafold":980},"structures":0,"taxa":1120},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":812},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}