{"metadata":{"accession":"PF02585","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR003737","hierarchy":null,"name":{"name":"GlcNAc-PI de-N-acetylase","short":"PIG-L"},"description":[{"text":"<p>Members of this family are related to PIG-L an N-acetylglucosaminylphosphatidylinositol de-N-acetylase ([ec:3.5.1.89]) that catalyses the second step in GPI biosynthesis [[cite:PUB00020119],[cite:PUB00031722]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00020119":{"PMID":10085243,"ISBN":null,"volume":"339 ( Pt 1)","issue":null,"year":1999,"title":"Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis.","URL":null,"raw_pages":"185-92","medline_journal":"Biochem J","ISO_journal":"Biochem. J.","authors":["Watanabe R","Ohishi K","Maeda Y","Nakamura N","Kinoshita T."],"DOI_URL":"http://dx.doi.org/10.1042/0264-6021:3390185"},"PUB00031722":{"PMID":12876312,"ISBN":null,"volume":"12","issue":"8","year":2003,"title":"Crystal structure of the conserved protein TT1542 from Thermus thermophilus HB8.","URL":null,"raw_pages":"1621-32","medline_journal":"Protein Sci","ISO_journal":"Protein Sci.","authors":["Handa N","Terada T","Kamewari Y","Hamana H","Tame JR","Park SY","Kinoshita K","Ota M","Nakamura H","Kuramitsu S","Shirouzu M","Yokoyama S."],"DOI_URL":"http://dx.doi.org/10.1110/ps.g03104003"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":224,"interactions":0,"matches":39343,"pathways":0,"proteins":39336,"proteomes":14450,"sets":0,"structural_models":{"alphafold":24676},"structures":28,"taxa":24217},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":55,"alignment:full":20044},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3dff","name":"The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2"}}}