{"metadata":{"accession":"PF02575","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR004401","hierarchy":null,"name":{"name":"YbaB/EbfC DNA-binding family","short":"YbaB_DNA_bd"},"description":[{"text":"<p>This is a family of DNA-binding proteins. Members of this family form homodimers which bind DNA via a tweezer-like structure [[cite:PUB00026293],[cite:PUB00057452],[cite:PUB00057453]]. The conformation of the DNA is changed when bound to these proteins [[cite:PUB00057453]]. In bacteria, these proteins may play a role in DNA replication-recovery following DNA damage [[cite:PUB00026293]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057452":{"PMID":19594923,"ISBN":null,"volume":"9","issue":null,"year":2009,"title":"DNA-binding by Haemophilus influenzae and Escherichia coli YbaB, members of a widely-distributed bacterial protein family.","URL":null,"raw_pages":"137","medline_journal":"BMC Microbiol","ISO_journal":"BMC Microbiol.","authors":["Cooley AE","Riley SP","Kral K","Miller MC","DeMoll E","Fried MG","Stevenson B."],"DOI_URL":"http://dx.doi.org/10.1186/1471-2180-9-137"},"PUB00026293":{"PMID":12486730,"ISBN":null,"volume":"50","issue":"2","year":2003,"title":"Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR.","URL":null,"raw_pages":"375-9","medline_journal":"Proteins","ISO_journal":"Proteins","authors":["Lim K","Tempczyk A","Parsons JF","Bonander N","Toedt J","Kelman Z","Howard A","Eisenstein E","Herzberg O."],"DOI_URL":"http://dx.doi.org/10.1002/prot.10297"},"PUB00057453":{"PMID":19208644,"ISBN":null,"volume":"37","issue":"6","year":2009,"title":"Borrelia burgdorferi EbfC defines a newly-identified, widespread family of bacterial DNA-binding proteins.","URL":null,"raw_pages":"1973-83","medline_journal":"Nucleic Acids Res","ISO_journal":"Nucleic Acids Res.","authors":["Riley SP","Bykowski T","Cooley AE","Burns LH","Babb K","Brissette CA","Bowman A","Rotondi M","Miller MC","DeMoll E","Lim K","Fried MG","Stevenson B."],"DOI_URL":"http://dx.doi.org/10.1093/nar/gkp027"}},"set_info":{"accession":"CL0717","name":"YbaB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":33,"interactions":0,"matches":24868,"pathways":0,"proteins":24833,"proteomes":16421,"sets":1,"structural_models":{"alphafold":16239},"structures":5,"taxa":24300},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":441,"alignment:full":11875},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"3f42","name":"Crystal structure of uncharacterized protein HP0035 from Helicobacter pylori"}}}