This is a family of hypothetical C. elegans proteins. The aligned region has no known function nor do any of the proteins which possess it. However, this domain is related to the CUB domain.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"CUB_domain","extract":"CUB domain is an evolutionarily conserved protein domain. The CUB domain is a structural motif of approximately 110 residues found almost exclusively in extracellular and plasma membrane-associated proteins, many of which are developmentally regulated. These proteins are involved in a diverse range of functions, including complement activation, developmental patterning, tissue repair, axon guidance and angiogenesis, cell signalling, fertilisation, haemostasis, inflammation, neurotransmission, receptor-mediated endocytosis, and tumour suppression. Many CUB-containing proteins are peptidases belonging to MEROPS peptidase families M12A (astacin) and S1A (chymotrypsin).
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0164","name":"CUB"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":37,"interactions":0,"matches":593,"pathways":0,"proteins":536,"proteomes":20,"sets":1,"structural_models":{"alphafold":523},"structures":0,"taxa":87},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":470},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}