{"metadata":{"accession":"PF02405","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR030802","hierarchy":null,"name":{"name":"Permease MlaE","short":"MlaE"},"description":[{"text":"<p>MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane [[cite:PUB00059298]]. In [swissprot:Q7DD59] it is involved in L-glutamate import into the cell [[cite:PUB00057443]]. In [swissprot:Q8L4R0] it is involved in lipid transfer within the cell [[cite:PUB00057443]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00057444":{"PMID":12743031,"ISBN":null,"volume":"22","issue":"10","year":2003,"title":"A permease-like protein involved in ER to thylakoid lipid transfer in Arabidopsis.","URL":null,"raw_pages":"2370-9","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Xu C","Fan J","Riekhof W","Froehlich JE","Benning C."],"DOI_URL":"http://dx.doi.org/10.1093/emboj/cdg234"},"PUB00057443":{"PMID":16495545,"ISBN":null,"volume":"74","issue":"3","year":2006,"title":"Identification of a meningococcal L-glutamate ABC transporter operon essential for growth in low-sodium environments.","URL":null,"raw_pages":"1725-40","medline_journal":"Infect Immun","ISO_journal":"Infect. Immun.","authors":["Monaco C","Tala A","Spinosa MR","Progida C","De Nitto E","Gaballo A","Bruni CB","Bucci C","Alifano P."],"DOI_URL":"http://dx.doi.org/10.1128/IAI.74.3.1725-1740.2006"},"PUB00059298":{"PMID":19383799,"ISBN":null,"volume":"106","issue":"19","year":2009,"title":"An ABC transport system that maintains lipid asymmetry in the gram-negative outer membrane.","URL":null,"raw_pages":"8009-14","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Malinverni JC","Silhavy TJ."],"DOI_URL":"http://dx.doi.org/10.1073/pnas.0903229106"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":43,"interactions":0,"matches":26428,"pathways":0,"proteins":26408,"proteomes":11914,"sets":0,"structural_models":{"alphafold":17443},"structures":22,"taxa":17526},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":528,"alignment:full":12500},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}