{"metadata":{"accession":"PF02016","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR040449","hierarchy":null,"name":{"name":"LD-carboxypeptidase N-terminal domain","short":"Peptidase_S66"},"description":[{"text":"<p>Muramoyl-tetrapeptide carboxypeptidase hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. The function of this activity is in  murein recycling. This family also includes the microcin c7 self-immunity protein [swissprot:Q47511]. This family corresponds to  Merops family S66.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00021060":{"PMID":16162494,"ISBN":null,"volume":"280","issue":"49","year":2005,"title":"Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with a Ser-His-Glu triad and a nucleophilic elbow.","URL":null,"raw_pages":"40802-12","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Korza HJ","Bochtler M."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.M506328200"},"PUB00020064":{"PMID":7559516,"ISBN":null,"volume":"270","issue":"40","year":1995,"title":"Chemical structure and translation inhibition studies of the antibiotic microcin C7.","URL":null,"raw_pages":"23520-32","medline_journal":"J Biol Chem","ISO_journal":"J. Biol. Chem.","authors":["Guijarro JI","Gonzalez-Pastor JE","Baleux F","San Millan JL","Castilla MA","Rico M","Moreno F","Delepierre M."],"DOI_URL":"http://dx.doi.org/10.1074/jbc.270.40.23520"},"PUB00020065":{"PMID":10428950,"ISBN":null,"volume":"18","issue":"15","year":1999,"title":"A defect in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli.","URL":null,"raw_pages":"4108-17","medline_journal":"EMBO J","ISO_journal":"EMBO J.","authors":["Templin MF","Ursinus A","Holtje JV."],"DOI_URL":"http://dx.doi.org/10.1093/emboj/18.15.4108"},"PUB00020063":{"PMID":8522520,"ISBN":null,"volume":"177","issue":"24","year":1995,"title":"Structure and organization of plasmid genes required to produce the translation inhibitor microcin C7.","URL":null,"raw_pages":"7131-40","medline_journal":"J Bacteriol","ISO_journal":"J. Bacteriol.","authors":["Gonzalez-Pastor JE","San Millan JL","Castilla MA","Moreno F."],"DOI_URL":"http://jb.asm.org/cgi/content/abstract/177/24/7131"}},"set_info":{"accession":"CL0014","name":"Glutaminase_I"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":31,"interactions":0,"matches":13365,"pathways":0,"proteins":13359,"proteomes":9836,"sets":1,"structural_models":{"alphafold":8109},"structures":37,"taxa":14121},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":188,"alignment:full":6559},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}